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Translational Research Interest Group
Our Theme: Bench to Bedside & Back
The purpose of the Translational Research Interest Group (TRIG) is to bring together physician scientists and basic research scientists to discuss efficient ways of accelerating the application of biomedical discoveries to clinical practice, ultimately for the benefit of patients. Conversely, it is also aimed to promote the translation of clinical observations to the development of improved preclinical strategies and disease models. The TRIG coordinates seminars and workshops to help bridge the gap between laboratory research and clinical applications. It also suggests topics and speakers for the Annual NIH Research Festivals, and nominates speakers for the NIH Wednesday Afternoon Lecture Series.
NIH intramural and extramural scientists are invited to become members of the TRIG. The invitation to join the TRIG is extended to staffs at the Food and Drug Administration and other Federal Government Agencies, and scientists from the extramural research community outside of Government. Please join our listserv and also add your name to our member list.
TRIG events are announced through the listserv and this website. The TRIG Chair is Minkyung (Min) Song.
Events in 2012-2013:
Visit "Meetings and Seminars" for complete schedule of the TRIG-hosted events and abstracts of lectures.
NIH Translational Research Interest Group Lecture Series
June 13, 2013 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Ena Wang, M.D.
Director of Molecular Science, Infectious Diseases and Immunogenetics Section
Department of Transfusion Medicine, NIH Clinical Center
“Genetic Inference about Cancer Immune Responsiveness”
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Forum on “Immunotoxins for Cancer Treatment: From Design to Clinical Success”
May 9, 2013 (Thursday) 1-3 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Ira Pastan, M.D.
NIH Distinguished Investigator; Institute of Medicine Member; Co-Chief, Laboratory of Molecular Biology, National Cancer Institute (NCI)
“Introduction to Recombinant Immunotoxins”
Robert J. Kreitman, M.D.
Head, Clinical Immunotherapy Section, Laboratory of Molecular Biology; Senior Investigator, NCI
“Treatment of Refractory Hairy Cell Leukemia with Moxetumomab pasudotox”
Alan S. Wayne, M.D.
Head, Hematologic Diseases Section; Senior Clinician, Pediatric Oncology Branch, NCI
“Treatment of Refractory Acute Lymphoblastic Leukemia in Children with Moxetumomab pasudotox”
Raffit Hassan, M.D.
Head, Solid Tumor Immunotherapy Section, Laboratory of Molecular Biology; Senior Investigator, NCI
“Treatment of Mesothelioma with Immunotoxin SS1P”
Ira Pastan, M.D.
“Future Directions”
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NIH Translational Research Interest Group Lecture Series
May 2, 2013 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Rajesh Ranganathan, Ph.D.
Director, Office of Translational Research, National Institute of Neurological Disorders and Stroke
“NINDS Accelerates Therapeutic and Device Discovery and Development”
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NIH Translational Research Interest Group Lecture Series
April 18, 2013 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Bibi Bielekova, M.D.
Chief, Neuroimmunological Diseases Unit, Neuroimmunology Branch, NINDS
“Can implementation of systems biology into clinical trials accelerate understanding of complex disease? Lessons from Multiple Sclerosis”
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NIH Translational Research Interest Group Lecture Series
March 14, 2013 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Crystal L. Mackall, M.D.
Chief, Pediatric Oncology Branch; Head, Immunology Section
Center for Cancer Research, NCI
“Developing Immunotherapies for Childhood Cancer”
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NIH Translational Research Interest Group Lecture Series
February 14, 2013 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Ludmila Prokunina-Olsson, Ph.D.
Investigator, Laboratory of Translational Genomics
Division of Cancer Epidemiology and Genetics, NCI
“Identification and characterization of a novel human interferon, IFNL4, and its role in human evolution and disease”
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NIH Translational Research Interest Group Lecture Series
January 10, 2013 (Thursday) 1-2 p.m., Bldg. 10 Room 2-C116
Gustavo Pacheco-Rodriguez, Ph.D.
Staff Scientist, Cardiovascular and Pulmonary Branch, NHLBI
“Molecular and Cellular Mechanisms of Lymphangioleiomyomatosis (LAM)”
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NIH Translational Research Interest Group Lecture Series
December 13, 2012 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Phil Skolnick, PhD, DSc (hon.)
Director, Division of Pharmacotherapies and Medical Consequences of Drug Abuse, NIDA
“Developing Drugs to Treat Substance Use Disorders (SUDs): Why Haven't We Been More Successful?”
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NIH Translational Research Interest Group Lecture Series
November 8, 2012 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
George Kunos, MD, PhD
Scientific Director of Intramural Research, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
“The peripheral endocannabinoid/CB1 receptor system is a novel therapeutic target for obesity, diabetes and fatty liver disease”
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NIH Translational Research Interest Group Lecture Series
October 25, 2012 (Thursday) 1-2 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Robert A. Star, MD
Director, Division of Kidney, Urologic and Hematologic Diseases, NIDDK
Senior Investigator and Chief, Renal Diagnostics and Therapeutics Unit, NIDDK
“Sepsis and Acute Kidney Injury: Kidney as amplifier and target”
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2012 NIH Research Festival
October 11, 2012 (Thursday) 12:00 p.m.-2:00 p.m.
Natcher Conference Center Room E1/E2
Symposium Session IV
“Common Molecular Mechanisms Underlying Pathogenesis and Treatment of Human Diseases”
Co-Chairs: Minkyung (Min) Song, PhD, NCI, and Joel Moss, MD, PhD, NHLBI
Speakers
Matthew Alkaitis, FARE Award Winner, NIAID
“Malaria Infection Depletes Erythrocyte Tetrahydrobiopterin, an Essential Cofactor for Nitric Oxide Synthesis"
Joel Moss, MD, PhD, NHLBI
“Mammalian Target of Rapamycin (mTOR) as a Target for Therapeutic Intervention in Diverse Diseases”
Ludmila Prokunina-Olsson, PhD, NCI
“From Cancer Genetics to Translational Genomics: Genetic and Functional Association of Prostate Stem Cell Antigen (PSCA) Gene with Several Cancers”
Gregory Kato, MD, NHLBI
“Pleiotropic Effects of Intravascular Hemolysis upon Vascular Homeostasis”
Emily Y. Chew, MD, NEI
“Treatment for Age-Related Macular Degeneration by Targeting Diverse Pathogenic Pathways”
David S. Goldstein, MD, PhD, NINDS
“Willie Sutton's Getaway Car and the Pathogenesis of Lewy Body Diseases”
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2012 NIH Research Festival
October 10, 2012 (Wednesday) 10:00 a.m.-12:00 p.m.
Natcher Conference Center Room F
Symposium Session II
“Health Disparities: Advances in Translational, Clinical, and Population Sciences”
Co-Chairs: Anil Wali, PhD, NCI, and Jeffrey Kopp, MD, NIDDK
Speakers
Cheryl Winkler, PhD, NCI
“Identification of APOL1 genetic variation explains much of the increased chronic kidney disease characteristic of African Americans”
Stefan Ambs, PhD, NCI
“A prognostic metabolome signature in breast tumors is linked to a distinct DNA methylation pattern in African-American and European-American patients”
Kevin Gardner, MD, PhD, NCI/CCR
"Molecular Linkages between Race, Obesity and Triple-negative Breast Cancer"
Charles Rotimi, PhD, NHGRI
“Ethnic Differences in lipid distribution: Implications for disease risk and response to treatment”
Cristina Rabadán-Diehl, PhD, MPH, NHLBI
“Health Disparities in Cardiovascular Disease: A Global Health Perspective”
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NIH Translational Research Interest Group Lecture Series
September 13, 2012 (Thursday) 1-3 p.m., Bldg. 10 (Clinical Research Center) Lipsett Amphitheater
Forum on “Discovery and Development of Therapeutic Candidates for Rare and Neglected Diseases at NIH”
John McKew, Ph.D.
Chief of the Therapeutic Development Branch and Director of Chemistry, NIH Center for Translational Therapeutics, National Center for Advancing Translational Sciences (NCATS)
“Public Private Partnerships to Advance Therapeutics for Rare and Neglected Diseases”
Marjan Huizing, Ph.D.
Head, Cell Biology of Metabolic Disorders Unit, Medical Genetics Branch, NHGRI
“N-acetylmannosamine (ManNAc) as a Therapy for Disorders of Hyposialylation”
Nuria Carrillo, M.D.
Staff Clinician, Therapeutics for Rare & Neglected Diseases (TRND), NCATS
“Translating ManNAc into a Therapy for Patients with Hereditary Inclusion Body Myopathy (HIBM)”
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